I think you will need to perhaps explain this a bit more. I'm not sure what you mean when you say "splitting your screen into 1, 2 or 3 zones".
Are you talking about the process of Recording screen activity? If so, you are able to select specific areas of the screen to record. But there can only be one area actually recorded.
Are you talking about the process of editing a video? If so, Camtasia allows you to crop media to different rectangular shapes.
Hopefully you see from my replies how more information is needed in order to know what you want. Mock ups or examples showing what you want to achieve will also help if you have them.